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InChiKey: HURFJQIYDCUMPC-UHFFFAOYSA-N
Formula: C18H20N2
CAS Number: 487020-03-1
3-d]pyrimidin-5-yl)benzonitrile
RU-SKI 43 Hydrochloride Size:Solid 2 mg InChiKey: HURFJQIYDCUMPC-UHFFFAOYSA-NRU SKI 43 is an inhibitor of Hat. It blocks palmitoylation of Shh without affecting palmitoylation of H Ras or Fyn, myristoylation of c Src, or acylation of Wnt3a. RU SKI 43 reduced pancreatic cancer cell proliferation and Gli 1 activation through Smoothened independent non canonical signaling. In addition, RU SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR. Product information CAS Number: 1782573 67 4 Molecular
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